Technically, Birkin isn't responsible for the T-Virus. James Marcus was. Birkin only developed the G-Virus.
I know I heard somewhere in RE2's dialogue that Birkin made the T-Virus... I don't know. I'll check the script.
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Also, it should be noted that in his first form, a single swing from his pipe is instant death. Even using a cheat device for invincibility won't protect you. You get hit with that pipe and you die. Period.
To tell you the truth, that's a major reason why I like the guy. That little glitch or whatever it was just made him seem so much more badass.
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