Is there any character that can take this 50k phy damage?

Assuming the 50k physical is dealt before a PvP reduction, it could be survivable.

50000 / 4 = 12500 // PvP reduction
12500 / 2 = 6250 // 50% Damage Reduction

Another druid can take this, or a Barbarian. Maybe a Sorc with an inventory of 70/15's and Synergized Energy Shield...